Professor F. Jon Kull

Dartmouth College, Department of Chemistry

Publications

· Reubold, T.F., Eschenburg, S., Becker, A., Kull, F.J., & Manstein, D.J. (2003) A structural model for actin-induced nucleotide release in myosin. Nature Structural Biology, 10(10):826-30.

· Holmes, K.C., Angert, I., Kull, F.J., Jahn, W. & Schröder, R.R. (2003) Electron cryo-microscopy reveals how strong binding of myosin to actin releases nucleotide. Nature, Sep 25;425(6956):423-7.

· Tsiavaliaris, G., Fujita-Becker, S., Batra, R., Levitsky, D.I., Kull, F.J., Geeves, M.A., Manstein, D.J. (2002) Mutations in the relay loop region result in dominant-negative inhibition of myosin II function in Dictyostelium. EMBO Rep. Nov;3 (11):1099-105.

· Kollmar, M., Kliche, W., Dürrwang, U., Manstein, D.M. & Kull, F.J. (2002) Crystal structure of the motor domain of a class-I myosin. EMBO J. Jun 3;21(11):2517-25.

· Kull, F.J. & Endow, S.J. (2002) Kinesin: switch I & II and the motor mechanism. J Cell Sci. 115: 15-23.

· Niemann, H.H., Knetsch, M.L.W., Scherer, A., Manstein, D.J. & Kull, F. J. (2001) Crystal structure of a dynamin GTPase domain in both nucleotide-free and GDP-bound forms. EMBO Journal. 21, 5813-5821.

· Kliche, W., Fujita-Becker, S., Kollmar, M., Manstein, D.M. & Kull, F.J. (2001) Structure of a genetically engineered molecular motor. EMBO Journal. 20, 40-46.

· Kull, F.J. (2000) The Kinesin Superfamily of Molecular Motors. Essays in Biochemistry: Molecular Motors. vol. 35, (Banting G & Higgin SJ, eds.). Portland Press, London.

· Sack, S., Kull, F.J. & Mandelkow, E. (1999) Motor proteins of the kinesin family: Structures, variations, and nucleotide binding sites. European Journal of Biochemistry. 262, 1-11.

· Kull, F.J., Vale, R.D. & Fletterick, R.J. (1998) The Case for a Common Ancestor: Kinesin and Myosin Motor Proteins and G Proteins. Journal of Muscle Research and Cell Motility. 19:877-886.

· Kull, F.J. & Fletterick, R.J. (1998) Is the Tubulin/FtsZ Fold Related to the G Protein Fold? Trends in Cell Biology. 8:306-307.

· Sablin, E.P., Kull, F.J. , Cooke, R., Vale, R.D. & Fletterick, R.J. (1996) Crystal structure of the motor domain of the kinesin-related motor ncd. Nature. 380:555-559.

· Kull, F.J. , Sablin, E.P., Lau, R., Fletterick, R.J. & Vale, R.D. (1996) Crystal structure of the kinesin motor domain reveals a structural similarity to myosin. Nature. 380:550-555.

· Fujiwara, S., Kull, F.J., Sablin, E.P., Stone, D.B. & Mendelson, R.A. (1995) The shapes of the motor domains of two oppositely directed microtubule motors, ncd and kinesin: a neutron scattering study. Biophysical Journal. 69(4):1563-1568.

· Eden, D., Luu, B.Q., Zapata, D.J., Sablin, E.P. & Kull, F.J. (1995) Solution structure of two molecular motor domains: nonclaret disjunctional and kinesin. Biophysical Journal. 68(4 Suppl):59S-64S.

· Vale, R.D., Coppin, C.M., Malik, F., Kull, F.J. & Milligan, R.A. (1994) Tubulin GTP hydrolysis influences the structure, mechanical properties, and kinesin-driven transport of microtubules. Journal of Biological Chemistry. 269(38):23769-23775.

Kull, F.J., Reed, M.F., Elgren, T.E., Ciardelli, T.L. & Wilcox, D.E. (1990) Solid-Phase Peptide Synthesis of the alpha- and beta Domains of Human Liver Metallothionein 2 and the Metallothionein of Neurospora crassa. Journal of the American Chemical Society. 112:2291-2298.